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Myxoma is the most common type of primary tumors of heart. Recurrence of nonfamilial myxoma is unusual and recurrence in left atrial appendage is not reported. We present a case of sporadic myxoma in the left atrium who had a successful resection. However, the patient’s constitutional symptoms caused confusion and difficulty in diagnosis. Final diagnosis was recurrent Myxoma in the left atrial appendage which was made through echocardiography. Echocardiography is a standard choice for noninvasive diagnosis and localization of heart tumors. Operative resection of tumors is the most appropriate treatment for myxoma.